HTHSCI 1H06 Lecture Notes - Lecture 2: Osteoporosis, Amenorrhoea, Hyponatremia

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Maintain flight of flight state: can adapt to the stress (i. e. cope) or resist (3 f"s, cortisol suppresses functions that are non essential/detrimental in a fight or flight response (e. g. sludd, reproduction, growth, immune etc. ) if you have a lot of stress, exhaustion, can lead to illness/death if one cannot eliminate or cope with the stressor mobilize energy stores in the body but cannot restore it. Diseases include: cushing"s, due to prolonged elevation of glucocorticoids (cortisol, the source of glucocorticoids may be, endogenous (acth secreting tumor, adrenal adenoma, exogenous (glucocorticoid administration, due to therapy of cortisol, a: will do down. Symptoms include: breakdown of muscle protein (atrophy, redistribution of body fat ( moon face , buffalo hump, weight gain (central obesity/hyperlipidemia/skin striae, hypertension, hyperglycemia, osteoporosis, taking energy away from growth. Symptoms include: weight loss, hypoglycemia, weakness, decreased serum na+ (hyponatremia, salt craving, dehydration because you cant reabsorb, hypotension.

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