HTHSCI 1H06 Lecture Notes - Lecture 1: Pattern Recognition Receptor, Smallpox Vaccine, Innate Immune System
20 Mar 2016
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What is the immune system: the immune system is the multi-layered host defence system that protects us against foreign invaders and endogenous threats. Latin~ immunities: protection from a duty to the state (ex/if u had immunities you were protected from military service or paying taxes) Best definition for immune system: the immune system is the most concerned with the maintenance of homeostasis . What does the immune system protect us against: pathogens~ bacteria, viruses, fungi, tumours, toxins~ snake venom, prions- malfolded proteins, allergins, many. Others: *know from chart, influenza & hiv are viruses, hiv causes aids, mycobacterium tb is a bacteria that causes tb. What are the 3 levels of immunity: intrinsic barriers~ pre-formed barriers that prevent infection, innate immunity~ immediate response & induced response, non specific, fast, fixed/constant (does not improve after same. Exposure: adaptive immunity~ very specific, slow, improves throughout response, immune memory. 4 intrinsic barriers: mechanical, chemical, physiological, & microbiological. Phase 1 of immune response: mechanical barriers.
