HTHSCI 1H06 Lecture Notes - Lecture 37: Thrombolysis, Vasoconstriction, Vasospasm

• School: McMaster University
• Department: Health Sciences
• Course: HTHSCI 1H06
• Professor: Alexander Ball

Document Summary

Most live a few hours - days. Pluripotent stem cell --> myeloid stem cell --> megakaryoblast --> megakaryocyte --> platelet. Stop blood loss form damaged blood vessels. Prevents hemorrhage (loss of a large amount of blood) from smaller blood vessels. Medical intervention usually required for hemorrhage from larger vessels. Coagulation = formation of brin threads platelet plug formation vascular spasm blood clotting. Platelets, brin and usually red blood cells. Cascade of reactions in which each clotting factor activates the next in a xed sequence. Clot plugs ruptured area of blood vessel. Platelets pull on brin threads causing clot retraction. Edges of damaged vessel are pulled together. Broblasts and endothelial cells repair the blood vessel. *diagram and abo blood group system chart in video* Rh antigen on rbc surface = rh+ Normally plasma does not contain anti-rh antibodies. Antibodies develop only in rh- blood type and only with exposure to the antigen.