HTHSCI 1LL3 Lecture Notes - Lecture 18: Main Source, Perfusion, Cytosol
9 Apr 2018
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Tricarboxylic acid cycle, electron transport chain and glycolysis. Atp = energy currency of the cell, molecule that provides energy that runs all biological processes. Triphosphate negatively charged, breaking the bonds apart to transport energy. Supply (carbs, lipids, and proteins) and demand (muscles, ion transport, etc) system. If the heart does not regenerate the atp supply it will become depleted within 1 minute. Each heartbeat uses 2% of the heart"s atp, the heart uses oxidative phosphorylation (aerobic method of generating energy more effective) Glucose pyruvate; when there is a mitochondria and oxygen, aerobic method of generating energy (oxidative phosphorylation) can occur through the tca cycle. When there is no mitochondria-- anaerobic glycolysis (no oxygen) occurs; creating lactate (which accepts electrons)-- a lot less atp is produced in this process-- occurs in the cytosol. When aerobic tissues have to use anaerobic functions build up of lactate (body is overwhelmed with acidity lower ph (acidosis)
