HTHSCI 1LL3 Lecture Notes - Lecture 4: Disulfide, Hydrogen Bond, Amine

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All the proteins in the body are made from the 20 amino acids coded for by our dna. We need protein in our diet to get the amino acids we need (some we can make, some we can"t) If a mutaion occurs there are diseases that arise. Enzymes are all proteins (with some excepions) The unique sequence of amino acids in each protein (the primary sequence) predicts its conformaion. If you get the wrong shape, a mutaion occurs (which can someimes cause a problem) The properies of side chains on each amino acid dictates the associaions between them leading to the conformaion of the protein. Primary structure: the exact list of aa. Secondary structure: is the elements of folding; ie alpha helices. Teriary structure: is how it folds in 3d space. Quaternary structure: is when you have muliple subunits. All of the 20 amino acids have a common structure.

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