HTHSCI 2F03 Lecture Notes - Lecture 11: Betahistine, Vestibular Schwannoma, Cyclizine

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Assoc. symptoms: n/v, hearing loss, tinnitus, nystagmus. Dilatation of endolymph spaces of membranous labyrinth (endolymphatic oedema) Attacks occur in clusters and last up to 12h. Impaired conduction anywhere between auricle and round window. Defects of cochlea, cohlear n. or brain. Benign, slow-growing tumour of superior vestibular n. Slow onset, unilat snhl, tinnitus vertigo. Mri all pts. c unilateral tinnitus / deafness. Ad condition characterised by fixation of stapes at the oval window. Hl improved in noisy places: willis" paracousis. Pta shows dip (caharts notch) @ 2khz. Anomalies of pinna, external auditory canal, tm or ossicles. Detection and mx of hearing loss before 6mo improves language. Malfusion accessory tags/auricles and preauricular pits, fistulae or sinuses. Sinuses may get infected, mimicking a sebaceous cyst. Can ischaemic necrosis of cartilage and subsequent fibrosis to cauliflower ears . Mx: aspiration + firm packing to auricle contour. Smooth, symmetrical bony narrowing of external canals. Secreted in outer 3rd of canal to prevent maceration.

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