HTHSCI 2H03 Lecture Notes - Lecture 1: Ear Drop, Central Cross-Island Highway, Ion

• School: McMaster University
• Department: Health Sciences
• Course: HTHSCI 2H03
• Professor: Kirsten Culver

Document Summary

The movement of a drug from its site of administration across body membranes, and into circulating fluids (bloodstream). P-glycoproteins that kick out the drugs out of the bloodstream. We may have to give more drug to combat this protein. (polar or ionized) then the drug can be administered iv, as it will dissolve in the blood. Iv drug administration skips the process of absorption. A fast onset of action can be expected. Mainly non-polar, non-ionized, or fat-soluble) then the drug cannot be administered iv. Oral administration is the most common form of drug administration. A slower onset of action should be expected. Drug has to dissolve & separate from the expient to be absorbed. Can enhance or slow the rate of dissolution. Slow releasing drugs are bound loosely tightly. If a patient chews the drug when it is supposed to be swallowed then it separates faster and increases the absorption.