HTHSCI 2H03 Lecture Notes - Lecture 9: Metformin, Weight Loss, Intrinsic Factor
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Hth sci 2h03 pharmacology of the endocrine system 2: drugs for the management of. Mechanism of action be made to attain target a1c levels within 6-12 months. If changes ar additional medications and insulin should be added. Inhibits the action of pancreatic alpha-amylase and intestinal al carbohydrate absorption. Lowers a1c by < 1. 0% study results: doses of 150 mg/d. Inhibits lipase in the intestine, thus delaying/inhibiting fat absorpti. Dyslipidemia is associated with decreased insulin sen. Weight loss is associated with increased insulin sensit. Risk of hypoglycemia is negligible when used as a monothera secretion/action. Enhances insulin sensitivity in liver and peripheral tissues by. Lowers a1c by <2. 0% study results: doses of 1500 mg/da. Risk of hypoglycemia is negligible when used as a stimulate insulin secretion; however, it may induce hypogl other drugs. Should not be prescribed in renal insufficiency - metformin i unchanged form.