HTHSCI 2H03 Lecture Notes - Lecture 20: Osteoporosis, Bone Resorption, Bone Fracture
10 Apr 2018
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Pharmacology of the endocrine system 4: drugs used for the treatment of osteoporosis lomoar cpsd| 2151316. In normal bone homeostasis, the rate of deposition will be roughly equal the rate of resorption. During childhood, adolescents and early adulthood, bone formation usually exceeds breakdown as the individual attains adult height and peak bone mass. After 35 years of age, the rate of bone resorption becomes greater than the rate of deposition. This shift in bone remodelling is a normal process of aging: dietary calcium: to keep our bones healthy, calcium is obtained through diet. However, only 30-50% of consumed calcium is absorbed in the intestine, the rest is lost in feces. The absorption of calcium in the intestine is increased in the presence of vitamin d, lactose, moderate amounts of fat, high protein intake, and physiological need. The absorption of calcium in the intestine is impaired in instances of vitamin d deficiencies, high fat diets, or diarrhea.
