HTHSCI 2H03 Lecture Notes - Lecture 17: Oxytocin Receptor, Ergometrine, Prostaglandin E2

• School: McMaster University
• Department: Health Sciences
• Course: HTHSCI 2H03
• Professor: J. Fader

Document Summary

Hth sci 2h03 pharmacology of the endocrine system 4: drugs used in pregnancy. Iv infusion: uterine response occurs almost immediately and. Im injection: uterine response occurs within 3 to 5 minutes and. Iv infusion: used for induction (to start labour) and a labour. Dose is increased every 15-60 minutes until a normal labo contractions of about 45 seconds each per 10 minutes) Im injection: used to prevent post-partum hem. Oxytocin binds to the adh receptor (at high concentr effect. This may lead to pulmonary edema, heart failure and water i considerations: monitor the patient for signs of edema and. Oxytocin infusion should be terminated if contraction longer than 90 seconds as these are signs of uterine hypert. This can lead to uterine damage or rupture and fetal oxyge. Fetal distress and maternal complications are also ind infusion. Clinical considerations: oxytocin receptors do not appear on t (at which point there is a 100-200 fold increase).