HTHSCI 2H03 Lecture Notes - Lecture 16: Endoplasmic Reticulum, Gs Alpha Subunit, Mammary Gland
10 Apr 2018
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Hth sci 2h03 pharmacology of the endocrine system 3: drugs for the female. Hormone replacement therapy combination estrogen and progestin hormone replacement therapy first used to treat ovarian failure and symptoms of. Replacing endogenous estrogen does not confer long-term health benefits. Whi trial (2002) indicate that hrt is associated with a small but significant increase risk of coronary artery disease, stroke, breast cancer, and deep vein thrombosis in menopausal women. The level of risk depends on the individual. Health history, age, number of years since start of menopause. Clinical considerations: the only benefit of hrt is relief of menopausal symptoms. Thus, if it is possible to treat these symptoms locally rather than systemically, we should try this first. Hrt should only be prescribed if it interferes with quality of life. Hrt should not be administered for more than. 5 years and should not be prescribed to women over the age of 59 years.
