HTHSCI 3K03 Lecture Notes - Lecture 1: Enterovirus 71, Open Reading Frame, Neurotropic Virus
12 Dec 2018
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Document Summary
Enterovirus 71 is a member of the enterovirus genus of the picornaviridae family. It is one of the causative agents of the hand-foot and mouth disease along with (cva16). Enterovirus 71 is also notable for its etiological role in the epidemics of severe neurological diseases in children. Hand, foot and mouth disease is generally considered to be a common exanthematous (ex-an-sir-metis) illness mostly seen in children under 5 years old. The infection is highly contagious and, in some cases, result in severe complications in the cns. The incident of hand-foot and mouth disease caused by ev 71 is less frequent; however, enterovirus. 71 is a neurotropic virus therefore, tend to be more severe and more likely to be associated with complications that can be fatal. 71 possesses a positive single-stranded rna genome of approximately. 7500 nucleotides consisting of a single open reading frame flanked by 5 and 3 end untranslated regions.
