KINESIOL 1A03 Lecture Notes - Lecture 4: Dense Irregular Connective Tissue, Bone Marrow, Adherens Junction

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Body tissue is divided in four basic types based on structure and function: epithelial tissue covers body surfaces and lines hollow organs, body cavities and ducts. Also form glands: connective tissue protects and supports the body and its organs. Epithelial develop from all three primary germ layers. Cell junctions contact points between the plasma membrane of tissue cells. Five most important types of cell junctions: tight junctions, adherens junctions, desmosomes, hemidesmosomes, gap junctions. Adherens junctions contain plaque, dense layer of proteins on the inside of the plasma membrane that attaches both to membrane proteins and to microfilaments (actin) of the cytoskeleton. Desomsomes contain plaque and have cadherins to extend into the intercellular space between adjacent cell membranes and attach cell to one another. Desomsome plaque attaches to elements of the cytoskeleton known as intermediate filaments that consist of the protein keratin e. g. stability of cells and tissue epidermis, cardiac muscle cells in the heart.

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