KINESIOL 1A03 Lecture Notes - Lecture 6: Bone, Trabecula, Osteoblast

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Bone cells: osteoblasts: produce collagen and proteoglycans (vesicles, form matrix vesicles of ca2+ and po4, release these vesicles bone matrix is formed, responsible for ossification (bone formation, osteochondral progenitor cells: stem cells that can become osteoblast or. Bone cells: osteocytes: osteocyte = osteoblast surrounded by bone matrix, also located in a cavity lacunae, considered inactive, maintain ability to produce components necessary to maintain bone matrix. Bone cells: osteoclasts: large multi nuclear cells, formed from fusion of monocytes, reabsorption of bone, acid and enzymes dissolve calcium, phosphorus and collagen, fragments are engulfed and digested. Classification of bone tissue: organization of collagen fibers within the bone matrix, woven bone, randomly oriented collagen fibers (development and repair, remodeled, lamellar bone, mature bone organized in sheets or layers (lamellae) Spongy (cancellous) bone: trabeculae connecting rods or plates, spaces filled with bone marrow and blood vessels, trabeculae oriented along the lines of stress.

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