KINESIOL 1A03 Lecture Notes - Lecture 11: Endoplasmic Reticulum, Myosin Head, Calcium Atpase
13 Feb 2016
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Document Summary
Wrap around myofibrils, at regular intervals, where actin/myosin. Map drops to t tubule, sense voltage changes, calcium sensed, released to myofibrils, to myofilaments, binds to troponin, move tropomyosin off active site, allows heads to bind. How we create movement of actin over myosin heads. Head of myosin bends to m line, detaches, reattaches to new active site, as long as calcium still bound , binds to z- During contraction of muscle, calcium binds to troponin, active sites exposed. Myosin attached to exposed sites, form cross bridges. Energy stored before moves head of myosin head of myosin, moves toward m-line. Atp binds to myosin head, detaches them from actin (rigormortus) After someone passes, muscles become stiff, release of calcium but no adp atp broken down to adp and phosphate, remain bound to myosin bound, ready. If ca+ still attached to troponin, cross bridge formation repeated, cycle occurs for next power stroke multiples times during contraction.
