KINESIOL 1AA3 Lecture Notes - Lecture 18: Glycogen, Insulin, Cytoplasm

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Autocrine: acts on the same cells that secreted them. Acts on distant targets: travels through blood. Regulates many things: extracellular fluid, metabolism. Ion balance: heart rate and blood pressure, blood glucose. Glands that secrete products into ducts: emptied into body cavities or body surface. Secretes products into bloodstream: other organs also secrete hormones as a 2nd function. Small and nonpolar: non polar low solubility. Bound to a binding protein: causes it to be more water soluble. Quickly diffuses out of capillaries: e. g. Mostly larger and polar: polar high solubility, mostly unbound. Some smaller and polar: mostly bound. Slowly diffuses out of capillaries: e. g. Half-life time required to eliminate half a substance from the circulation: lipid soluble long half life, water soluble short half life. Interaction with the target cell: lipid soluble binds to a nuclear receptor, water soluble binds to a membrane receptor. Dramatic and irregular hormone concentrations: e. g. Regular intervals and hormone concentrations: e. g.

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