KINESIOL 1AA3 Lecture Notes - Lecture 9: Haldane Effect, Medulla Oblongata, Brainstem

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Membrane thickness: thin membrane easier diffusion. Diffusion coefficient of gas: measures how easily gas diffuses into and out of liquids and tissues, affected by solubility and size of the molecule. Surface area: alveoli shape maximum surface area. Partial pressure differences: gas moves from high pressure to low pressure. Each gas in a mixture of gases will exert its own pressure: total pressure = sum of partial pressures, partial pressure the pressure exerted by each type of gas in a mixture. Proportion of each gas stays constant: only total atmospheric pressure changes, high o2 in atmospheric air, low co2 in atmospheric air. Gas concentration in a liquid is also determined by its solubility coefficient: how easily a gas dissolves in liquid. Nitrogen has low solubility: makes it hard to enter the blood, even though it has high partial pressure. Co2 has high solubility: easily brought into blood. O2 has low solubility: requires high partial pressure.

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