KINESIOL 1YY3 Lecture Notes - Lecture 13: Proprioception, Intercostal Muscle, Dorsal Respiratory Group

• School: McMaster University
• Department: Kinesiology
• Course: KINESIOL 1YY3
• Professor: Krista Howarth

Document Summary

S-shaped bc when hemoglobin molecule is completely saturated, it has a high affinity for oxygen: this is at level of lungs when we actually want to get oxygen onto hemoglobin. As oxygen is removed form hemoglobin it changes the shape of the hemoglobin molecule; doesn"t bind on to the rest of oxygens as tightly > can more easily remove the next > shape change again > etc. Situations where we need more oxygen levels > exercise: need a large partial pressure change to remove the first o2, drops at the level of the tissues! Effect of ph, temp, and co2, and o2 release. More hydrogens bound on hemoglobin > affinity for hgb decreases >>> bohr effect : also works when lactic acid release. Co2o same mechanism as ph: bohr effect. Hypothermia > lefward shif (higher affinity for o2, slower delivery of o2)