LIFESCI 3A03 Lecture Notes - Lecture 2: Phosphatase, Inositol Trisphosphate, Diglyceride
Document Summary
Tallest man, due to hyperplasia of the pituitary gland. Results in an excess of cells producing growth hormone. This caused a high amount of grown hormone to be released: contrast with: leonel messi: Short stature, with opposite condition; a poor ability to produce growth hormone. He was supplemented with a hormonal treatment to improve his growth, funded by his skill: both of the above examples showed issue with production rather than acceptance of signal. This is where small molecules pass though (ions/lipids) and go to a neighbouring cell. Paracrine: occurs by extracellular secretion of signal. Endocrine: similar to paracrine but occurs over long distances through blood stream. Synaptic: occurs across nervous synapse using neurotransmitters. Chemicals involved: they can be hydrophobic or hydrophilic. It brings about a desired cellular response: open/close channels, activate a 2nd messenger, or modify gene expression. Both share some chemical messengers (like norepinephrine and epinephrine)