LIFESCI 2A03 Lecture 3: Life Sci 2A03 Lecture 3 notes
23 Feb 2017
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Relationship of probability and uncertainty, 5% rule <5% of chances, and still successful then results are significant. Purpose of randomization and replication in experimental design. Regeneration: the reactivation of development of tissues later on in life. Invertebrate animals like hydra, or anemone, most animals with radial symmetry. Bidirectional regeneration ability to generate whole bodies from small tissue fragments. Hydra cut in half two new hydra that are smaller will regenerate (seen in plants) Planaria non-parasitic flatworm that exhibits an extraordinary ability to regenerate. Regeneration in planaria: muscular contraction to limit size of cut surface, thin wound epithelium forms over surface, accumulation of undifferentiated cells (neoblasts) in the blastemal. Blastema an aggregation of cells in early embryo capable of differentiation into specialized cells. Small undifferentiated mitotic cells that comprise about 20% of the worms body they act as stem cells for growth and regeneration: growth and differentiation of blastemal. How do neoblasts cells in the blastemal know what to do.
