LIFESCI 2A03 Lecture 1: lecture 1- introduction

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RESEARCH METHODS IN LIFE SCIENCE
LIFESCI 2A03 FALL 2018
INTRODUCTORY LECTURE
Aim: to explore the scientific method
Check course outline for course details
LEARNING OUTCOMES
Describe and differentiate the different steps of the scientific method
Effectively postulate hypotheses, predictions and experiments to test
them
Critically analyze and interpret experimental results
Present and describe data and interpretation in an oral and written
formal
TOPIC: STEM CELL RESEARCH
Hot topic due too public and media attention via political and ethical
discussions
Innovative techniques used
REGENERATION:
Mythology vs real life
o An old fashioned idea seen in Greek mythology
o Octopi have the ability to regenerate limbs, extra tentacle = a result
of abnormal regeneration?
Regeneration in lower vertebrates
o Lizards and salamanders can regenerate lost tails and appendages
Regeneration in invertebrates
o Planarian: flatworms with a remarkable ability to regenerate
o Each cut piece will regenerate into an entire flatworm
Regeneration in humans
o The livers ability to regenerate seems to have been known since
ancient times
ROLE OF STEM CELLS IN CANCER & AGING
The ability of resident stem cells to maintain and repair organs
diminishes with age, whereas paradoxically the risk of cancer increases
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