LIFESCI 2G03 Lecture Notes - Lecture 2: Genetic Testing, Zygosity
23 Mar 2018
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P (roll a 6 and a 4) = (1/6)(1/6) + (1/6)(1/6) = 2/36 = 1/18. P (two same numbers) = p (two 6s) = 1/6 --> many same numbers therefore. The probability of two independent events happening simultaneously is the product of their individual probabilities. If diploid individuals carry two alleles and only one allele is passed onto the egg/sperm, we can liken this to a flip of a coin with two sides: There is biological fluctuation (49:51, 52:48) but it"s not unlikely 99:1 would be weird. Probability of inheriting d allele from dad and d allele from mom (1/2)(1/2) = 1/4. P (all no symptoms) = (3/4)^4 = 81 /256. A pedigree analysis: the study of an inherited trait in a group of related individuals to determine the pattern and characteristics of the trait. Sex, marriages leading to children, siblings, we are only following one gene. Indicates the generations, sex, deceased, label 1,2,3 from left to right.
