LIFESCI 4W03 Lecture Notes - Lecture 2: Peanut Oil, Kyphosis, Vitamin D Deficiency
20 Sep 2016
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Document Summary
Low bone mass + micro-architecture deterioration: resulting in fragility and risk of fractures. Diagnosis based on bone mineral density (bmd: 1sd decrease in bmd (any site), increase fracture risk by 50% Hunchback of the upper spine of the back. Problem: change in quality of life (impaired or restricted respiration, restricted. Usually occur from a fall from standing height. In canada, it costs ,000 per hip fracture. Prior wrist fracture: clinical sign that bones may be weakening. Low body weight (<60 kg: which means these individuals have a low lean mass (musculature, may indicate loss of muscle, more prone to falls. High alcohol intake (3 or more units daily: poorly understood, may decrease bone formation. Being a woman: high estrogen, low testosterone. Anabolic to muscle cells and bone health. Therefore, has a stimulatory effect on osteoblasts (bone formation cells) Testosterone stimulates the formation of bone cells, and since woman have reduced testosterone leading to fewer bone forming cells.
