MEDRADSC 2S03 Lecture Notes - Lecture 7: Anal Canal, Gastrointestinal Tract, Glycemic Index

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Rare (4% of all cancers of the lower gi tract) 3 major prognostic factors are site (anal canal vs perianal skin), size (t>2cm better), and nodal status. From anal verge to anorectal ring (~4 cm) Age: similar to colorectal ca median age = 60 yrs, 30-90 years reported. Higher annual incidence in african americans: but majority of patients are non-hispanic whites. In most areas of the world anal canal ca is seen in more women than men, except in areas with a relatively high proportion of homosexual men (ie. san franciso: geneital warts, may be related to hiv, smoking. Symptoms: asymptomic, rectal bleeding (most common symptom, perineal pain, change in diameter of stool (pencil stool, tenesmus mass sensation at the anus, pruritis (itching, a. *most patients with anal canal ca are diagnosed early stage (73% diagnosed with stage 0 ii) at an. Squamous cell ca: basal cell carcinoma (basaloid transition cell, a subset of squamous cell carcinomas, adenocarcinoma, malignant melanoma.

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