MEDRADSC 2S03 Lecture Notes - Lecture 3: Combined Oral Contraceptive Pill, Breast Cancer, Ionizing Radiation
24 Jun 2016
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Document Summary
Breast cancer is the most common cancer in women. ~1 in 8 women will develop breast cancer. Since 1993, canadian incidence rates for breast cancer have stabilized and death rates have declined. Since 1997 incidence rates have dropped because many post-menopausal women stopped using long-term hormone replacement. In 2008 an estimated 5400 deaths from breast cancer. Gender: <1% occur in men; female:male = 100:1. Geography: incidence in oriental countries and mexico is much lower than the n. Behavioural: high weight: bmi >33kg/m2; fat stores extract estrogen, not linked to oral contraceptives ( birth control pill); o. Tobacco: night shift work not enough amount of melantonin. Ionizing radiation exposure (atomic bomb survivors, treatment for. Hodgkin"s disease - develops in young adult, female patients that have been treated with radiation develop bc) Estrogen - early menarche (<12 yrs), late menopause (>45/50): nulliparous (no children) or later pregnancy (>35 yrs),
