MEDRADSC 2X03 Lecture Notes - Lecture 4: Nuclear Membrane, Dna Replication, Chromatid

• School: McMaster University
• Department: Medical Radiation Sciences
• Course: MEDRADSC 2X03
• Professor: Sandra Charbonneau

Document Summary

If critical (and non-redundant) molecule of cell is damaged, cell survival is threatened. Dna is main target for radiation damage to occur in order to cause biological effects. Viability: the ability to replicate and divide. Ladder rungs are purine and pyrimidine base pairs attached to sugar. Responsible for: directing cell activity transmitting hereditary information of cell. If we damage rungs or base pairs, it might have a negative effect on the info. House genes in specific linear sequences on chromatin threads structure: ce(cid:374)t(cid:396)al co(cid:374)st(cid:396)ictio(cid:374) (cid:858)ce(cid:374)t(cid:396)o(cid:373)e(cid:396)e(cid:859, two arm extensions (chromatids) Human somatic (non-germ) cells contain 23 pairs of chromosomes. Second gap/resting phase first gap/resting phase, i(cid:374)(cid:448)e(cid:374)to(cid:396)y check, ca(cid:374) stop if (cid:449)e do(cid:374)(cid:859)t ha(cid:448)e the (cid:396)ight tools. Dna synthesis: chromosome duplicates its dna, 2 chromatids joined at centromere. Parent cell divides to form 2 daughter cells identical to the parent cell. Creation of chromosomes from coiling of chromatin threads. Centrioles move to opposite poles of cell.