MEDRADSC 1B03 Lecture Notes - Lecture 7: Nuclear Membrane, Diplo, Complex Cell
12 Feb 2018
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Spiral (not actually one category, just description) Microbes: small organisms visible only with a microscope. Simple structure, lack nuclear membrane, complex cell wall (except for mycoplasmas) Complex structure, dna enclosed in nuclear membrane, lack cell wall (except plants and fungi) Aerobic: grows in a presence of oxygen. Anaerobic: grows in an absence of oxygen. Cell wall: shape, protection, gram negative or positive (identify treatment) Cell membrane: semi permeable, allow nutrients in and out. Capsule/slime layer: additional protection, or interfere with phagocytosis from wbc or macrophages. Human cells do not have a cell wall, but bacteria do. Therefore human cells are not affected by penicillin but bacteria are attacked. Can get immune response, used as toxoid. Produced by gram negative bacteria, released after death. Capillary permeability (++ fluid lead to interstitial spaces causing endotoxic shock) Antibiotics kill cell wall , but endotoxins released after death Ex. destroy rbc (hemolysins), break down collagen (collagenase), dissolve blood clots (streptokinase)
