MEDRADSC 1B03 Lecture Notes - Lecture 2: Stratified Squamous Epithelium, Heart Failure, Hepatectomy
3 Sep 2018
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Document Summary
Cells have mechanisms by which they can adapt their growth & differentiation to altered conditions in the body. Tissues are frequently modified as a response to hormonal stimulation or environmental stimuli (ie irritation) Disease may develop when cell structure & function change & homeostasis cannot be maintained as a result. Cells may be damaged/destroyed by changes in metabolic processes, reduced levels of atp, altered ph in the cells, or damage to the cell membrane & receptors. There are 5 ways cells may adopt to change. Looking at a normal cell & the environment it is within: atrophy. Shrinkage of an organ/body part due to the shrinkage in the size of its cells. Less use of the tissue, insufficient nutrition, decreased neurologic/hormonal stimulation, & aging. Ovaries tend to shrink throughout menopause; skeletal muscle decreases when a limb is immobilized in a cast for several weeks: hypertrophy.
