MEDRADSC 2I03 Lecture Notes - Lecture 16: Ankylosing Spondylitis, Osteoarthritis, Atlanto-Axial Joint

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Dislocation of one thumb (left), subluxation of the other (right) Steroids and anti-inflammatory drugs, finger implants (synthetic joints), medical botox (temporary) not as far along as the previous. Periarticular surfaces of the joints ha(cid:448)e osteope(cid:374)i(cid:272) (cid:894)(cid:271)o(cid:374)e loss, that"s (cid:449)hy it"s so (cid:271)la(cid:272)k(cid:895) A: normal, black arrow, anterior arch (odontoid right behind) B: there is a space between anterior arch of c1 and c2 (this view is with flexion risky) Unknown cause (maybe linked to genes) non-suppurative (non-infectious) Primarily small joints of hands and feet, very serious when it affects the spine (c1/c2) Can be progressive or can have periods of remission. Crippling deformity so there is disuse, bone density decreases (osteopenic/fractures) Will be bilateral (will be both hands) Progresses towards trunk then to every joint. Inflammation of synovial membrane causes erosion of articular cartilage underlying bony cortex and ligaments: can develop ankyloses: bony fusion across joint.

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