MEDRADSC 2S03 Lecture Notes - Lecture 2: Esophagus, Stratified Squamous Epithelium, Signet Ring Cell

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The gi tract is a continuous, muscular. Digestive juices produced by glands in the lining of the stomach. Pre-cancerous tumours polyps, gists (gi stromal tumours), lipomas. 95% adenocarcinomas start in the gastric mucosa (inner lining) Produces enzymes and bile to help digest food; proteins to help blood clot; cleanses the blood. Hcc hepatocellular carcinoma arises from the liver cells hepatocytes. Small pear shaped organ under the liver. Stores bile from the liver and releases it into the small intestine. 85% adenocarcinomas start in lining of gb. Rare types: signet ring cell, clear cell carcinomas. Knowledge of lymphatics helps direct diagnostic and staging, as well as treatment. Thin-walled 25cm long tube lined with epithelium. Begins just inferior to the laryngopharynx at cricoid cartilage (c6), at the upper esophageal. Lies posterior to the trachea and anterior to bodies esophageal hiatus. Passes through the diaphragm by the and ends at the gastroesophageal (ge or eg) junction at t10-11.

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