MEDRADSC 2T03 Lecture Notes - Lecture 1: Heterotopic Ossification, Myositis Ossificans, Joint Replacement
27 Jun 2016
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Presence of bone in soft tissue where bone doesn"t normally exist 1. Primitive mesenchymal cells in connective tissuse to osteoblastic tissue and osteoid 3. Examples in skin, skeletal muscle, fibrous tissue, subcutaneous tissue, and even blood vessels. Extremely variable because ho isn"t always clinically significant and patients live without ever knowing they have this condition. Following traumatic brain injuries 11% (ranges reported from 10-20%) Following spinal cord injuries 20% (ranges reported from 20-40%) As of 2005, there were 400 patients known in the u. s. with genetic forms of heterotopic ossification. There is no uniform agreement concerning the etiology and pathogenesis of heterotopic ossification. Has been known to most likely occur in 5 clinical settings. 5 clinical settings: genetic: fibrodysplasia ossificans progressive (fop) and progressive osseous. These lesions occur in three clinico-radiologic settings: 1) bizzare parosteal osteochondromatous, 2) florid reactive periositis, and 3) subungual exostoses. http://www. physio-pedia. com/heterotopic_ossification.
