MEDRADSC 2T03 Lecture Notes - Lecture 14: Vaginal Cancer, Epithelium, Adventitia
Document Summary
Exposure to miscarriage prevention drug prone to clear cell adenocarcinoma. Atypical cells in vagina vaginal intraepithelial neoplasia (increased risk of cancer) caused by hpv. Vagina: muscular tube that connects uterus with outer genitals (7. 5-10 cm long); located in lower abdominal area, between the bladder and rectum. The walls are usually collapsed so that they touch each other; because of their multiple folds, it allows the vagina to expand during sexual intercourse and childbirth. Occurs commonly in cells that line surface of vagina. Early vaginal cancer may not cause any signs and symptoms. Unusual vaginal bleeding (after intercourse, or after menopause, b/w menstrual periods, after vaginal douching) Change in bladder habits: burning or pain during urination, blood in urine. Change in bowel habits: blood in the stool, constipation, painful bowel movements. Medical history: smoking, exposure to diethylstilbestrol before birth, vaginal, vulvar, cervical precancerous conditions, previous cancers, hiv. Endoscopy (cystoscopy, uteroscopy, sigmoidoscopy) check for spread.