NURSING 3PA2 Lecture Notes - Lecture 37: Klebsiella, Surfactant Protein D, Elastin

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Systemic inflammation continued: acute phase proteins linked to copd symptoms and severity: crp, fibrinogen, serum amyloid. The following acute phase proteins, plasma concentrations can be increased in persons with. Increased crp has been linked to health and exercise capacity and appears to be a significant predictor of bmi. If crp remains high two weeks after an exacerbation, there is a likelihood of recurrent exacerbation. Fibrinogen plasma concentrations are increased with frequent exacerbations. Worse expiratory volume in one second and increased risk of hospitalization with copd was linked with elevated plasma fibrinogen. An elevated serum amyloid a during an exacerbation correlated with the severity of exacerbations. Lastly, surfactant protein d better related disease severity and symptoms in crp. Both crp and fibrinogen have been associated with increased cardiac comorbidity: systemic manifestations and comorbidities: skeletal muscle weakness, cachexia, lung cancer, pulmonary hypertension, ischemic heart disease, cardiac failure, osteoporosis, normocytic anemia, diabetes, obstructive sleep apnea and depression.

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