NURSING 3SS3 Lecture Notes - Lecture 4: Surviving Sepsis Campaign, Case Fatality Rate, Sofa Score

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Sepsis is a life-threatening condition that affects many children regardless of some underlying healthcare issues. Sepsis is one of the leading causes of death among children. The management of pediatric sepsis was comprehensively advocated through systematic review process in the surviving sepsis campaign guidelines, however, many recommendations and suggestions were still based on low quality evidence. Unfortunately, this change in the definition is only applied to adults. Prevalence is steadily increasing from 1995-2005 by 81% The case fatality rate dropped from 10. 3-8. 9% Patients with invasive infection, sepsis, and septic shock accounted for 6. 9%, 2. 9%, and. 2. 1%, respectively, of the total icu admissions: the icu mortality rate was 3. 9%, 5. 6%, and 17. 0% in each diagnostic group, which were much higher than 3. 0% of overall icu mortality in children. Hartman et al. reported a decreasing proportion of severe sepsis children with underlying comorbidities in 2005 compared with 2000 and 1995. Neuromuscular, cardiovascular, and respiratory disorders were the most common comorbidities.

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