NURSING 2PF3 Lecture 5: N2PF3A Pathophysiology Module 5- Inflammation Part I

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Inflammation can be innate (natural/present at birth) or acquired (evolving over time) Inflammation: a protective response designed to eliminate the initial cause of injury, remove damaged tissue and generate new tissue; the biochemical and cellular response of vascularized tissue to injury designed to protect the body from further injury. Goals of inflammation: movement of all necessary blood and cell components to the site of injury, delivery of nutrients and blood cells to eradicate the offender, dilution, confinement and elimination of the offending agents. Stimulation and facilitation of components of the immune system. Promotion of healing with generation of new tissue. Increased metabolic rate; when called upon to fight injury the cells step up daily routines and increase production of necessary items increase heat production, oxygen and glucose consumption and production of waste. Increased capillary permeability; allows for movement of wbcs (specifically neutrophils), proteins and nutrients into the tissue.

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