NURSING 2PF3 Lecture Notes - Lecture 9: Oncotic Pressure, Peripheral Edema, Transcellular Fluid

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Some particles such as glucose and electrolytes move from the vessel into the interstitial space and create interstitial colloidal osmotic pressure, pulling a small amount of fluid into the interstitial space. Excess interstitial fluid is taken up by the lymphatics and returned to the central circulation. Fluid imbalances at the capillary level can be due to several alterations in normal fluid movement. Increased capillary hydrostatic pressure can cause higher amounts of fluid to leave the capillary. If hydrostatic pressure continues to be high at the venous end of the capillary, net fluid movement will be out of the capillary. Edema is the accumulation of fluid in the interstitial space. Third-spacing transcellular fluid accumulation; subdivision of the extracellular fluid compartment, including joint spaces, pericardial and pleural cavities, peritoneum and ocular fluid; non-functional fluid is trapped due to obstruction to lymphatic flow or inability to be pushed/pulled out. The signs and symptoms of edema are determined by its location:

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