NURSING 3PA2 Lecture Notes - Lecture 14: Monocyte, Arteriole, Serous Fluid

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Inflammation is the protective reaction of vascularized tissue to local injury. Acute inflammation is the early (almost immediate) reaction of tissue to the injury, and it is the first phase of wound healing. Acute inflammation can be triggered by cell or tissue damage, or by the presence of dead cells or noxious agents such as bacteria. Acute inflammation typically occurs before the immune response becomes established, and aims primarily at removing the injury-causing agent and limiting the extent of tissue damage. Acute inflammation occurs in two overlapping stages: vascular and cellular. In the vascular stage, arterioles and venules near the site of injury constrict briefly and then dilate. Dilation promotes congestion while an accompanying increase in capillary permeability leads to the movement of fluid into the affected tissue, resulting in the five classic signs of inflammation: redness, swelling, heat, pain, and loss of function.

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