BIOC 1430 Lecture Notes - Lecture 15: Acetyl-Coa, Dihydroxyacetone Phosphate, Carbohydrate Metabolism

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Digestion is the breakdown of food molecules into smaller, simpler molecules by hydrolysis. These simpler molecules can be used by cells for their metabolic needs. Beings in the mouth; enzymes alpha-amylase catalyzes hydrolysis of glycosidic linkages in starch and glycogen. Very little digestion of carbohydrates in mouth. Not much digestion of carbohydrates in stomach. Alpha-amylase is inactivated by acidic environment of the stomach. Main site for digestion is in the small intestine. Alpha-amylase secreted by the pancreas breaks down polysaccharide to disaccharide. Final step in carbohydrate digestion occurs on the outer membranes of intestinal mucosal cells. Maltose 2 glucose units (enzyme maltase) 3 major products of carbohydrate digestion: glucose, fructose and galactose. These monosaccharides are absorbed into the blood stream thought the intestinal wall. The folds of the intestinal wall are lined with finger-like projection called villi which are rich in blood capillaries though which the absorption takes place. Metabolic pathway by which glucose (6c) is converted to pyruvate (3c)

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