BIOL 102 Lecture Notes - Lecture 9: Digestive Enzyme, Phospholamban, Protein Kinase
12 Jan 2016
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Document Summary
Lets signaling molecules to pass from one cell to another (heart. Molecules bound to cell surface serve as signals (nerve-muscle muscle) contact) Cells secrete signaling molecules that bind to themselves or similar neighbouring cells. Signal doesn"t affect secreting signal but influences cells in area. Signals (hormones) travel long distances and are longer lasting (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) Activated receptor stimulates a series of pathways that form the signal transduction pathway. Cellular response ( in reference to the signal transduction pathway) Alter activity of 1 or more enzymes. Binding and release between receptor and ligand are fast. Causes intracellular domain to become a catalyst. G-protein releases gdp & binds to gtp. Gpcr affects vision, smell, immunity, behavior etc. (animals) Ligand binding causes ion channels to open and ions to flow through membrane. Animals signal between nerve and muscle cells (cid:1) Passes through membrane and binds to receptor in nucleus.
