BIOL 103 Lecture Notes - Lecture 36: Crispr, Keystone Species, Mitochondrion
Document Summary
Close interactions between species over their life histories are called symbioses. Symbioses can always benefit one species, but have different outcomes on the second: Parasites have a deleterious impact upon their host. Mutualists exist in relationships that are beneficial to both species. Commensalism involves a benefit to one species with no impact upon the other. Marrelli et al. found that malaria mosquitoes suffer a major fitness cost to feeding on hosts circulating gametocytes. When they acquire gametocytes via feeding apparatus, gametocytes block the feeding apparatus and prevent feeding => major fitness cost. If feed on gametocyte carrying host, fertility goes down => may be immune system response. Genetically engineered malaria mosquitos so that it inhibits passage of plasmodium to gut. Crispr proteins snip that piece of dna so they can be replaced w/ healthy genes. +/+ symbioses are hard to find and to verify. Mitochondria was originally parasitic rlsp that became mutualistic.