BIOL 205 Lecture Notes - Lecture 5: Wild Type, Harriet Creighton, Centromere

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Independent assortment of genes on different chromosomes at meiosis is one way to shuffle allele combinations: how do we detect recombination, previous ways, we compared the inputs into meiosis with the outputs. In diploids, recombinants are best detected in a testcross: have a pure line homozygous a and homozygous b, both wildtype allele crossed with a homozygous a and b, both null alleles. Mendel or the chromosomal theory: although all of me(cid:374)del"s (cid:1011) ge(cid:374)es sho(cid:449)ed i(cid:374)depe(cid:374)de(cid:374)t asso(cid:396)t(cid:373)e(cid:374)t, se(cid:448)e(cid:396)al (cid:449)e(cid:396)e o(cid:374) similar chromosomes. In the early 1900s william bateson and r. c. Punnett studying inheritance of two factors (genes) i(cid:374) peas (cid:272)a(cid:396)(cid:396)ied out sta(cid:374)da(cid:396)d f1 dih(cid:455)(cid:271)(cid:396)id self (cid:272)(cid:396)osses (cid:271)ut it did(cid:374)"t sho(cid:449) the. 9:3:3:1 ratio as predicted by the principle of independent assortment, and suggested that the factors were coupled (linked: the (cid:272)o(cid:374)fi(cid:396)(cid:373)atio(cid:374) of bateso(cid:374) a(cid:374)d pu(cid:374)(cid:374)ett"s h(cid:455)pothesis had to await the development of. Thomas hunt morgan found a similar deviation from.

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