BIOL 206 Lecture Notes - Lecture 11: Effective Population Size, Population Bottleneck, Genetic Drift

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1)sampling error in populations: founder effects, genetic drift, effective population size, sampling error underlies random evolutionary processes *** Random biases from small samples: the probability of the biases(random fluctuation) decreases very strongly as the population increases. It will not favour one allele over another. Indiviudal outcomes are difficult to predict but the average (or groups of outcomes) outcome is much more predictable: random episodes. Founder effect (1) new population from small number of colonists (2) allele rfequencies amoung colonists not representative of source population. Probability of losing an allele via founder effect (fe: assume source population at hwe. F(aa)=p^2 , f(aa)=2pq, f(aa)=q^2: p(cid:396)o(cid:271)(cid:894)o(cid:374)l(cid:455) a(cid:895) a(cid:373)ou(cid:374)g (cid:858)(cid:374)(cid:859) (cid:272)olo(cid:374)ists = (cid:894)p^2(cid:895)^(cid:374, p(cid:396)o(cid:271)(cid:894)o(cid:374)l(cid:455) a o(cid:396) o(cid:374)l(cid:455) a(cid:895) a(cid:373)ou(cid:374)g (cid:858)(cid:374)(cid:859) (cid:272)olo(cid:374)ists = (cid:894)p^2(cid:895)^(cid:374) + (cid:894)(cid:395)^2(cid:895)^(cid:374) The probability of fixing an allele by fe. As the allele increases in freq, the prob of it beign the only allele. As we increase the number of colonist there is a very rapid reduction of.

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