PHGY 214 Lecture Notes - Lecture 33: Extracellular Fluid, Indium Phosphide, Oncotic Pressure

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Sites of exchange b/n blood and surrounding tissue cells: max sa and min diffusion distance. Velocity of blood flow trhu capillaries is relatively slow provides adequate exchange time. Two types of passive exchange: diffusion (mvmt of ions not protein, bulk flow (flow needed by solutes dissolved in water, water allows tissue entities to be dissolved. Velocity of flow inversely prop to total cross-sectional a of all vessels at any given level of the circ system. Blood flow rate vs velocity of flow to total x-sectional a. As sa increases blood flow v decreases. Narrow, water filled gaps life at junctions b. n cells. Lipid soluble sub readily pass thru endothelial cells by dissolving in lipid bilayer. Size of pores varies from organ to organ, can change depending on conditions of organ. Exchange: plasma protein dn cross capillary wall. Many cap are not open: so u dn waste blood on region of body that dn need it.

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