PHGY 350 Lecture Notes - Lecture 10: Ligand-Gated Ion Channel, Lesion, Tectorial Membrane

• School: Queen's University
• Department: Physiology
• Course: PHGY 350
• Professor: Allan R Baer

Document Summary

Bra in de pe nds on a s upply of o2 a nd glucose. Re s ponds to local co 2, ph, blood pre s s ure. Circle of willis: ana s tomos e s provide a lte rna te pa thwa ys. Re pe rfus ion is s ue s. Lipid-s oluble mole cule s cros s e a s ily. Impe rme a ble to la rge a nd cha rge d mole cule s: ex. Co 2, ba rbitura te s a nd a lcohol. Development issues: bbb not fully forme d a t birth. Kernicterus bilirubin cros s e s bbb. Ma y a llow e ntry of wbcs. Circula te s through ve ntricle s , s uba ra chnoid s pa ce. Abs orbe d by a ra chnoid villi into ve nous s inus e s.