PHGY 214 Lecture Notes - Lecture 3: Resting Potential, Goldman Equation, Nernst Equation
12 May 2016
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Document Summary
All living cells have a membrane potential that allows for cellular communication in nervous tissue and muscle. Is the different in the relative number of cations (+) and anions (-) in the icf and ecf. Magnitude of potential depends on the number of opposite charges separated. Neurons have membrane potential of -60 mv. A movement in the negative (-) direction: hyperpolarization - a movement in the neg- ative (-) direction even more than resting potential. * ions responsible for the resting membrane potential are na+, k+, and anions. the concentration gradient for k+ will always be outward and the concentration gradient. 3 na+ out for every 2 k+ it transports in un- a membrane potential with the outside becoming relatively equal transport generates more positive. * the sign always designates the polarity of the excess charge on the inside of the membrane. Effect of the na+ pump on membrane potential same as k+ but in the opposite direction.
