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6 Pages

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PSYC 271
Monica Valsangkar- Smyth

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L4: NEURAL CONDUCTION & SYNAPTIC TRANSMISSION Feb 2/12 1. Resting Membrane Potential - Microelectrodes are thin electrodes – one is placed inside the neuron and the other tip in the extracellular fluid - The resting potential is -70mV - It exists because + and – ions are distributed unequally on the two sides of the neural membrane. - There are 4 factors that determines the ionic distribution of the resting potential - Ions in solution are in random motion so there can be an accumulation Random Motion of a particular class of ions in one area - This increases the probability that random motion moves ions out of the area because there are more ions available to leave or not move more ions into the area because there are fewer ions available to come in. Electrostatic Pressure - Like charges repel and opposite charges attract, thus, electrostatic pressure disperses any accumulation of + or – charges in an area. Differential Permeability of - Ions pass through membrane at special pores called ion channels. When Membrane neurons are at rest the membrane is resistant to K+/Cl- ions
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