BLG 144 Lecture Notes - Lecture 4: Genetic Marker, Genotype Frequency, Wild Type
27 Jan 2017
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Key concepts: gene flow is movement of alleles from one population to another, mutation is o(cid:374)e of the (cid:271)ase pai(cid:396)s s(cid:449)it(cid:272)hi(cid:374)g to a(cid:374)othe(cid:396) (cid:271)ase pai(cid:396). It"s the o(cid:374)ly (cid:449)ay you (cid:272)a(cid:374) (cid:373)ake a (cid:271)(cid:396)a(cid:374)d (cid:374)e(cid:449) allele. 4 mechanisms: natural selection, genetic drift, gene flow, mutation. Biologists take 3 approaches to study these mechanisms. They create mathematical models that predict the fate of alleles over time under various conditions. They are interested in seeing change in a particular genotype: apply those results. We have a model, observation, and we apply the results to solve those problems. They wanted to now what happened when all the individuals of the population randomly bred: came up with this concept of gene pool, gene pool: all those alleles all together for a particular trait . Deriving the hardy-weinberg principle: a1 is represented by p. Sum of p and q should add up to 1. Sum of all the frequencies of all the genotypes together.
