BMS 150 Lecture Notes - Lecture 2: Genetic Disorder, Ribonucleotide, Messenger Rna

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Many victims had secondary respiratory infections of pneumonia. Mice injected with live cells of the r strain do not get pneumonia and do not die. Mice injected with live cells of the s strain get pneumonia and die. Mice injected with heat killed s cells do not get pneumonia and do not die. Mice injected with live r cells and heat killed s cells get pneumonia and die. The r transformed with the s and became toxic again. Turned out that the transforming part was dna. James watson and francis crick discover the structure of dna. Described the structure of dna based on roasline. Franklins x ray that she took of dna chromosomes showing its actually shape. Is composed of two nucleotide chains running in opposite directions and wound into a helix. The backbone is composed of alternating deoxyribose sugar and a phosphate group. All nucelotides contain a base a sugar (two) and a negatively charged phosphate group.

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