FNN 100 Lecture Notes - Lecture 9: Phosphocreatine, Hypophosphatemia, Hyperphosphatemia
Document Summary
Fnn module 6 bone building nutrients part ii. Phosphate is what is measured in the body. 85% in bone and teeth rest in soft tissue. In tissues its part of molecules with both structural and regulatory roles. Meat, fast food, cheese, milk, canned fish, and cola. Mechanisms: passive diffusion, active transport facilitated by vit d. Controlled by vit d and p transporters. Levels are not as strictly controlled as calcium. Maintained in conjunction with ca for bone mineralization. When blood levels are low triggers active vit d increases absorption and reabsorption of p and ca from bone. High intakes increases urine loss wont affect blood levels too much. When pth not secreted, p is retained by kidneys and ca is excreted. Ca and p react in opposite ways. Exception is plant seeds (contain p as phytic acid) Some foods contain phytase which helps p become more available. Inhibitors: phytic acid/phytate, p binding antacids, large doeses of ca.