PAT 20A/B Lecture Notes - Lecture 11: Bacteriostatic Agent, Insomnia, Lipophilicity

• School: Ryerson University
• Department: Pathotherapeutics
• Course: PAT 20A/B
• Professor: Susan Bishop

Document Summary

Adrenergic beta2 receptor agonist bronchodilator local, site-specific effects on the larger central airways including bronchodilation and prevention of bronchospasms. Results in bronchodilation by inhibiting acetycholine at its receptor sites, thereby blocking cholinergic bronchomotor tone (bronchoconstriction); also abolishes vagally mediated reflex bronchospasm triggered by cigarette smoke, dusts, cold air, and a range of inflammatory mediators (eg. histamine). In the bronchial airways, it exhibits inhibition of muscarinic receptors of the smooth muscle resulting in bronchodilation. Quick acting, selective beta2-adrenergic receptor agonist, acts prominently on smooth muscles of trachea, bronchi, uterus, and vascular supply to skeletal muscles. Produces bronchodilation by relaxing smooth muscles of bronchial tree. Bronchodilation after inhalation of tiotropium is predominantly a site- specific effect. Blurred vision, difficulty in accommodation, bitter taste, dry oropharyngeal membranes, cough, exacerbation of symptoms, rash, hives, urinary retention, headache. Non-specific chest pain, dependent edema, dry mouth, dyspepsia, pharyngitis rhinitis, sinusitis, upper respiratory tract infection.